Two 4-week randomized, double-blind, placebo-controlled trials were conducted in 163 pediatric subjects aged from birth to 48 months with symptoms of bronchospasm associated with obstructive airway disease (presenting symptoms included: wheeze, cough, dyspnea , or chest tightness). VENTOLIN HFA or placebo HFA was delivered with either an AeroChamber Plus® Valved Holding Chamber or an Optichamber® Valved Holding Chamber with mask 3 times daily. In one trial, VENTOLIN HFA 90 mcg (n = 26), VENTOLIN HFA 180 mcg (n = 25), and placebo HFA (n = 26) were administered to children aged between 24 and 48 months. In the second trial, VENTOLIN HFA 90 mcg (n = 29), VENTOLIN HFA 180 mcg (n = 29), and placebo HFA (n = 28) were administered to children aged between birth and 24 months. Over the 4-week treatment period, there were no treatment differences in asthma symptom scores between the groups receiving VENTOLIN HFA 90 mcg, VENTOLIN HFA 180 mcg, and placebo in either trial.
This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Advair HFA Inhaler. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using Advair HFA Inhaler.
Medical experts believe that asthma is caused due to genetic disposition of the individuals. However the environmental factors and the allergens as well as pollutants too contribute as triggers and aggravators of asthmatic attacks in patients. In terms of treatment of asthma, there are several approaches that have been adopted by the medical community. Short term and fast acting treatment is prescribed to patients to control and provide immediate relief to the patients at the instance of asthmatic attack. The doctors advise asthmatic patients to always carry albuterol with the inhaler with them all the time. In case of asthmatic attack, albuterol can effectively provide relief within fifteen minutes by relaxing the muscles and freeing the air passage to fecilitate free breathing and remove chest congestion. Albuterol is the first line of treatment prescribed by the doctors in all cases. Apart from the short term treatment option involving albuterol, the doctors advise long term medication in the form of Corticosteroids and Long acting beta-adrenoceptor agonists. For emergency relief, doctors use intravenous treatment involving magnesium sulfate etc.