Drugs that work on your immune system. Your doctor may consider these medicines -- such as azathioprine, cyclosporine, or methotrexate -- if other treatments don’t help. There are also prescription creams and ointments that treat eczema by controlling inflammation and reducing immune system reactions. Examples include pimecrolimus (Elidel), which is a cream, and crisaborole (Eucrisa) and tacrolimus (Protopic), which are ointments. You should only use these for a short time if other treatments don't work -- and you should never use them on kids younger than 2, according to the FDA.
Lots of unsubstantiated alternative eczema therapies are promoted in the press. Be wary of these claims. Miraculous natural cures for eczema often contain crushed cortisone tablets. Evening Primrose oil (or gamolenic acid), flaxseed & omega 3 oils offer no real additional benefit to eczema. Chinese herbal tea extracts have been evaluated but taste unpleasant and may even cause liver toxicity. Recalcitrant eczema on the face may respond to non-steroidal immune-modulator preparations such as Tacrolimus (Protopic) and Pimecrolimus (Elidel) however skin redness may be a temporary side effect. Ultra-violet light therapy treatment has been helpful so get out into the sunshine! There is growing proof that lactobacillus GG probiotics (Reuterina) supplemented in pregnancy, breastfeeding and early in life may reduce eczema in babies by altering their gut immune reactivity.