Yes, you should check that Mirena is in proper position by feeling the removal threads. It is a good habit to do this once a month. Your healthcare provider should tell you how to check that Mirena is in place. First, wash your hands with soap and water. You can check by reaching up to the top of your vagina with clean fingers to feel the removal threads. Do not pull on the threads. If you feel more than just the threads or if you cannot feel the threads, Mirena may not be in the right position and may not prevent pregnancy. Use non-hormonal back-up birth control (such as condoms and spermicide) and ask your healthcare provider to check that Mirena is still in the right place.
Newer medications help reduce the time it takes to fall asleep. Some of these sleep-inducing drugs, which bind to the same receptors in the brain as do benzodiazepines, include Lunesta , Sonata , and Ambien . They are somewhat less likely than benzodiazepines to be habit-forming, but over time can still sometimes cause physical dependence. They can work quickly to increase drowsiness and sleep. Another sleep aid, called Rozerem , acts differently from other sleep medicines by affecting a brain hormone called melatonin, and is not habit-forming. Belsomra is another unique sleep aid that affects a brain chemical called orexin , and is not addictive or habit-forming.
The areas of the brain where cannabinoid receptors are most prevalently located are consistent with the behavioral effects produced by cannabinoids. Brain regions in which cannabinoid receptors are very abundant are the basal ganglia , associated with movement control; the cerebellum , associated with body movement coordination; the hippocampus , associated with learning , memory, and stress control; the cerebral cortex , associated with higher cognitive functions; and the nucleus accumbens , regarded as the reward center of the brain. Other regions where cannabinoid receptors are moderately concentrated are the hypothalamus , which regulates homeostatic functions; the amygdala , associated with emotional responses and fears ; the spinal cord , associated with peripheral sensations like pain; the brain stem , associated with sleep , arousal , and motor control; and the nucleus of the solitary tract , associated with visceral sensations like nausea and vomiting .