The oral use of stanozolol can also have a profound impact on levels of SHBG (sex hormone-binding globulin). This is a characteristic of all anabolic/androgenic steroids, however its potency and form of administration make Winstrol particularly noteworthy in this regard. Since plasma binding proteins such as SHBG act to temporarily constrain steroid hormones from exerting activity, this effect would provide a greater percentage of free (unbound) steroid hormone in the body. This may amount to an effective mechanism in which stanozolol could increase the potency of a concurrently used steroid. To further this purpose one could also addition Proviron, which has an extremely high affinity for SHBG. This affinity may cause Proviron to displace other weaker substrates for SHBG (such as testosterone), another mechanism in which the free hormone level may be increased. Adding Winstrol and Proviron to your next testosterone cycle may therefore prove very useful,, markedly enhancing the free state of this potent muscle building androgen.
Winstrol is hepatotoxic, and because of this, it should be used at the lowest effective dose for the shortest possible cycle. What’s more, you should consider using a supplement designed to provide some additional protection. Milk thistle is a highly recommended option; studies suggest it can provide an effective layer of protection when it is used for the entire length of your cycle. There are some other supplements on the market, such as Liver Care, which are blends of natural ingredients that have been shown to work together to prevent liver toxicity.